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Pseudomonas 1

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Impacts of n-alkane concentration on soil bacterial community structure and alkane monooxygenase genes

Yueqiao Liu, Aizhong Ding, Yujiao Sun, Xuefeng Xia, Dayi Zhang

Frontiers of Environmental Science & Engineering 2018, Volume 12, Issue 5, doi: 10.1007/s11783-018-1064-5

Abstract:

Soil microbial community is not significantly shaped by alkane concentrations

Alkane concentrations alter dominant alkanedegraders in soils

Different alkanes are preferentiallydifferent contamination level

Different types of alkanemonooxygenase genes responsible for alkane degradation

Keywords： Petroleum hydrocarbon contaminated site n-alkane contamination level n-alkane biodegradation Soil bacterialcommunity Alkane degraders Alkane-monooxygenase genes

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Discovery of small molecule degraders for modulating cell cycle

Frontiers of Medicine Pages 823-854 doi: 10.1007/s11684-023-1027-5

Abstract: In this article, we aim to summarize the latest developments of CDKs and cyclin protein degraders.Additionally, possible methods are discussed for the development of degraders for CDK members that stillthis article provides a comprehensive summary of the latest advancements in CDK and cyclin protein degraders

Keywords： PROTAC molecular glue degrader cell cycle CDK cyclin

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Selective pseudosolubilization capability of

Fei HUA, Hongqi WANG

Frontiers of Environmental Science & Engineering 2013, Volume 7, Issue 4, Pages 539-551 doi: 10.1007/s11783-013-0498-z

Abstract: Pseudosolubilized ability of sp. DG17 on -alkanes, role of biosurfactants in -octadecane uptake and trans-membrane transport mechanism of -octadecane were studied by analyzing amount of pseudosolubilized oil components in water phase, and the fraction of radiolabeled C -octadecane in the broth and cell pellet. GC-MS results showed that pseudosolubilized oil components were mainly C to C of -alkanes. In -octadecane broth, pseudosolubilized -octadecane could be accumulated as long as pseudosolubilized rate was faster than mineralization rate of substrate, and the maximum concentration of pseudosolubilized -octadecane achieved to 45.37 mg·L . All of these results showed that sp. DG17 mainly utilized alkanes by directly contacting with pseudosolubilized small oil droplets in the water phase. Analysis of C amount in cell pellet revealed that an energy-dependent system mainly controlled the trans-membrane transport of -octadecane.

Keywords： Pseudomonas alkane uptake pseudosolubilization trans-membrane transport